Cholesterol domains enhance transfection

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Artificial cavitation nuclei significantly enhance acoustically induced cell transfection.

The efficiency of ultrasound-mediated gene transfection was enhanced three- to fourfold, compared to previous results, through the use of green fluorescent protein reporter gene, cultured immortalized human chondrocytes and artificial cavitation nuclei in the form of Albunex. Cells were exposed to 1.0-MHz ultrasound transmitted through the bottom of six-well culture plates containing immortaliz...

متن کامل

Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux.

Published data related to both cell membrane biology and apolipoprotein structure are reviewed and used to formulate a new model describing the mechanisms of cholesterol efflux from cell plasma membrane to high density lipoprotein (HDL) particles. The central premise of this model is the existence of heterogenous domains of cholesterol within plasma membranes. We propose that cholesterol efflux...

متن کامل

Proposing New Methods to Enhance the Low-Resolution Simulated GPR Responses in the Frequency and Wavelet Domains

To date, a number of numerical methods, including the popular Finite-Difference Time Domain (FDTD) technique, have been proposed to simulate Ground-Penetrating Radar (GPR) responses. Despite having a number of advantages, the finite-difference method also has pitfalls such as being very time consuming in simulating the most common case of media with high dielectric permittivity, causing the for...

متن کامل

Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes.

A major gap in our knowledge of rapid hepatic HDL cholesterol clearance is the role of key intracellular factors that influence this process. Although the reverse cholesterol transport pathway targets HDL to the liver for net elimination of free cholesterol from the body, molecular details governing cholesterol uptake into hepatocytes are not completely understood. Therefore, the effects of ste...

متن کامل

After ENHANCE: is more LDL cholesterol lowering even better?

After much speculation, to the point of congressional involvement, regarding the reasons for the delay in reporting the results of a relatively small trial of carotidartery imaging in patients with familial hypercholesterolemia (FH), a brief top-line synopsis was released this year on January 14 (1 ). The study, called ENHANCE (Effect of Combination Ezetimibe and High-Dose Simvastatin versus Si...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Therapeutic Delivery

سال: 2013

ISSN: 2041-5990,2041-6008

DOI: 10.4155/tde.13.16